She's definitely joining the talk show ranks. Not only do you have the end of Oprah Winfrey's show at play, but there might be a few more openings/shakeups in daytime TV.
Although right now I think Ellen DeGeneres is an excellent position to become the number-one daytime talk show, with Oprah's show ending and Regis announcing his retirement.
Somebody made a joke about Katie going to NPR. Why not, if they'd have her?